I feel the pagination method demonstrated here is advantageous in that regard, eliminating vertical motion while allowing to see parts of two "pages" at the same time:

http://www.magicscroll.net/

I would love to have that on my ebook reader, may need to hack that together some time to try. I dislike switching back and forth between two pages as is sometimes necessary; in this regard, this even seems better to me than a regular book.