http://binaryelysium.com/blog/2011/12/13/a-reluctant-relatio...
Did you mean 2 factor authentication?
Google + 2 step authentication + Yubikey
Is there any reason why you can't do this? It seems like it would work? (I've never used Yubikey so I might be missing something)
source: http://support.google.com/accounts/bin/answer.py?hl=en&a...