20% of people invest in stocks, and these people control almost 50% of wealth in America. A major goal of QE is to pump the market up to generate a wealth effect for these people, and (hopefully) pull the economy up with it. You can see that this happened by checking out the SPY chart from Nov. 2008 (QE1) onward.
As the other commenter noted, don't fight the Fed. Contrary to what you read in the popular media, they know what they are doing. If you hopped on board in '08, you got massive returns the past few years.
Technical Analysis is your only friend.
Or to put it another way; if the fed is pumping money into the market it only makes it easier for others to exit.