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We haven't found anything in nature that resembles reverse-mode automatic differentiation, either in evolution or in neuroscience.


What would that look like. Is there an implementation of the finite difference method in biology somehow?


I'd be surprised.


Yeah thanks, me too. So I'm wondering what point 22 is getting at. How could that even be possible?


Biology can use discrete methods; we have discrete neurons (and other cells), discrete chemical species like ATP, discrete amino acids, discrete genes made of discrete nucleotides, etc.


Fur sure. But I don't get how that leads to an expectation that our biology is computing and utilizing derivatives in a computational graph.

Point 22 seems to imply that the other finds it notable that that isn't happening.


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