There are two components to anti-biotic use that are taken together very harmful. The first as has been amply described by the author is the flat over use of anti-biotics where they are not needed. The second and perhaps more relevant human example is that humans tend not to finish their full course of anti-botics allowing resistant mutations to gain a greater foot hold. Other than long acting or implanted delivery mechanisms I am not sure that we can ever really ensure compliance with the full regimen in all patients.